Ethnicity's Influence on Breast Cancer

It's been suspected in the past, but now we finally have proof: Women who are diagnosed with breast cancer fall into different groups, and these differences are not just related to the stage of disease or their personalities.

These differences are based on their ethnicity, and ethnic differences can actually determine how well a cancer responds to particular drugs.

This discovery — that cure rates can depend in part on ethnicity — is a new challenge for doctors, since the majority of clinical trials have been conducted only on Caucasian women in North American, Europe, and Australia.

The knowledge that such differences exist among racial groups has now forced researchers to include in their research databases the ethnicity of participants in clinical trials. Scientists must now know if one drug works better for one group than for another.

Breast cancer is predominantly a disease of the economically developed world, but rates are rising in Asia and economically developing countries. Different ethnic groups also have different incidences of certain types of breast cancer, regardless of where they live. (Basal-type breast cancer is more prevalent in African-American and West-African women, for example)

Read More..

It possible to have depression and anxiety at the same time?

Q:
Is it possible to have depression and anxiety at the same time?
A:
Anger and Depression: Can Omega-3 Fatty Acids Help?

Anxiety disorders can take many different forms — including panic attacks, specific phobias, generalized anxiety and obsessive-compulsive disorder — each with its own distinct set of symptoms.

However, depression is generally categorized by a core set of symptoms, including pervasive sadness, fatigue, irritability, sleep difficulties, decreased interest in usually enjoyable activities and sometimes suicidal thoughts. Some of these same symptoms may be seen with anxiety disorders — with the main feature of anxiety disorders being unreasonable fear and worry.

An anxiety disorder may predispose you to developing depression and vice versa. Fortunately, treatments for depression may provide relief for anxiety as well.

If you have symptoms of either or both of these problems, it's important to consult with a mental health provider who can assist you in sorting out these conditions and what treatments may be most helpful for you.

Last Updated: 05/18/2007

© 1998-2008 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "Mayo Clinic Health Information," "Reliable information for a healthier life" and the triple-shield Mayo logo are trademarks of Mayo Foundation for Medical Education and Research. Terms of use.

Read More..

Home Treatment


There are ways to improve your symptoms of restless legs syndrome at home.

Try:

  • Exercise. Regular, moderate exercise may reduce symptoms. Avoiding long periods between activity or sudden bursts of intense activity may also be helpful. Talk to your doctor before starting an exercise program.
  • Heat or cold. Your symptoms may be relieved by bathing in very hot or very cold water. Applying a heating pad or ice bag to your legs may also help symptoms.
  • Changing your sleep schedule. Fatigue can make your symptoms worse. Because symptoms typically improve around 4 a.m. to 6 a.m., try going to bed later than usual or allowing extra time for sleeping in to help you get the rest you need.
  • Stretching and massage. You may be able to control your symptoms by gently stretching and massaging your legs before bed or as discomfort begins.

Avoid:

  • Caffeine and alcohol. These may make your symptoms worse.
  • Certain drugs. It may help to avoid antidepressants, antihistamines, cold and sinus medicine, antipsychotic medicine, and certain antinausea drugs (metoclopramide or prochlorperazine). Taking products that contain these ingredients may make your symptoms worse. Your doctor needs to know what medicines you are taking in order to rule them out as a cause of your symptoms.
  • Being confined for long periods. Try to plan for situations where you will need to remain seated for long stretches. For example, if you are traveling by car, plan to make occasional stops so you can get out and walk around.
  • Excessive exercise. Although moderate exercise may help relieve symptoms, unusually intense workouts may make them worse. Try to identify at what level exercise helps and at what point it triggers restless legs syndrome.

See your doctor if your symptoms do not improve, if they become worse, or if they significantly interfere with your sleep and daily functioning.

Read More..

Topic Overview

What is restless legs syndrome?

Restless legs syndrome (RLS) is a disorder related to sensation and movement. People with restless legs syndrome have an unpleasant feeling or sensation in their legs when they lie down to sleep. Most people also have a very strong urge to move their legs, and moving the legs sometimes makes them feel better. But all this movement makes it hard or impossible to get enough sleep.

When you don’t get enough sleep, you may start to have problems getting things done during the day because you're so tired. You may also be sleepy or have trouble concentrating. So it’s important to see your doctor and get help to manage your symptoms.

What causes restless legs syndrome?

Usually there isn't a clear reason for restless legs. The problem often runs in families. Sometimes there is a clear cause, like not getting enough iron. If that’s the case, treating the cause may solve the problem.

Women sometimes get restless legs while they are pregnant. The problem usually goes away after the baby is born.

Other problems that are sometimes linked to restless legs syndrome include kidney failure, rheumatoid arthritis, diabetes, nerve damage, anemia, and Parkinson's disease. But most people who seek treatment do not have any of these other problems.

What are the symptoms?

Restless legs syndrome makes you feel like you must move your legs. These feelings are often described as tingling, "pins and needles," prickling, pulling, or crawling.

Moving your legs will usually make your legs feel better, at least for a short time. This problem usually happens at night when you are trying to relax or go to sleep.

After you fall asleep, your legs may begin to jerk or move. These movements are called periodic limb movements. They can wake you from sleep, which adds to your being overtired. Although periodic limb movement is considered a separate condition, it often happens to people who have restless legs syndrome.

How is restless legs syndrome diagnosed?

One of the hardest parts of having restless legs syndrome is getting to the diagnosis. Often doctors don’t ask about sleep or don’t ask about the symptoms of restless legs. If you're not sleeping well, or if you think you may have restless legs syndrome, tell your doctor.

Your doctor will talk with you about your symptoms to make sure that the feelings in your legs you describe are typical of restless legs syndrome and not caused by some other problem.

You may have blood tests to rule out other problems that could be causing your symptoms. In some cases, the doctor may order tests of your nerves to be sure there is no nerve damage. Your doctor may also order a sleep study called a polysomnography. This test records how often your legs jerk or move while you sleep.

How is it treated?

If your symptoms are mild, a few lifestyle changes may be enough to control your symptoms. Some changes that may help:

  • Avoid tobacco, alcohol, and caffeine.
  • Keep your bedroom cool, quiet, and comfortable, and use it only for sleeping, not for watching TV.
  • Get regular exercise.
  • Massage the leg or the arm, or use heat or ice packs.

When symptoms are more severe, medicines may help control your leg movements and help you sleep. There are different types of medicine, and you may have to try a few to find the one that works best.

Frequently Asked Questions

Learning about restless legs syndrome:

Being diagnosed:

Getting treatment:

Ongoing concerns:

Read More..

Downsizing Your Breasts: A New Surgical Approach to Breast Cancer

I'm seeing a growing number of women who've had to undergo a big lumpectomy of one breast and so have opted to have a surgical reduction on the other, healthy breast, so as to achieve symmetry.

This is because a large lumpectomy must remove not only the cancerous lump but also, just to be safe, a wide margin of the non-cancerous cells around it. So, some women decide to have twin surgeries that accomplish 2 objectives at once:

  • They rid their body of the source of the cancer.
  • They get a bilateral breast reduction that restores symmetry.

In some cases, the margins are so wide, and the cancer so small, that some women may not need to have any post-lumpectomy radiation, too. Wow, another plus!

And to get even more bang from the (insurance company's) buck, a study conducted several years ago showed that breast reductions in general reduced the risk of breast cancer in women who were at high risk, either from a previous personal or family history of cancer.

So, all around, this is a wonderful and increasingly popular option for some women. Good deal!

Read More..
Template by - Abdul Munir | Daya Earth Blogger Template